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Title: Treatment of tetracycline antibiotics by laccase in the presence of 1-hydroxybenzotriazole
Authors: Suda, Tomoyo
Hata, Takayuki
Kawai, Shingo
Okamura, Hideo
Nishida, Tomoaki
Journal Title: Bioresource technology
Publisher: Elsevier
Journal Volume: 103
Journal Issue: 1
Start Page: 498
End Page: 501
Issue Date: 2011-10-20
Rights: Copyright © 2011 Elsevier Ltd. All rights reserved.
NDC: 464
Abstract: Tetracycline antibiotics are widely used in human and veterinary medicine; however, residual amounts of these antibiotics in the environment are of concern since they could contribute to selection of resistant bacteria. In this study, tetracycline (TC), chlortetracycline (CTC), doxycycline (DC) and oxytetracycline (OTC) were treated with laccase from the white rot fungus Trametes versicolor in the presence of the redox mediator 1-hydroxybenzotriazole (HBT). High performance liquid chromatography demonstrated that DC and CTC were completely eliminated after 15min, while TC and CTC were eliminated after 1h. This system also resulted in a complete loss of inhibition of growth of Escherichia coli and Bacillus subtilis and the green alga Pseudokirchneriella subcapitata with decreasing tetracycline antibiotic concentration. These results suggest that the laccase-HBT system is effective in eliminating tetracycline antibiotics and removing their ecotoxicity.
ISSN: 09608524 OPAC
E-ISSN: 18732976 OPAC
Publisher's DOI: 10.1016/j.biortech.2011.10.041   
PMID: 22071243
Journal NCID: AA11522750 OPAC ciniib
Textversion: author
Appears in Collections:06. 雑誌論文・記事(Journal Article, Article, Preprint)

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Others By: Suda, Tomoyo -- Hata, Takayuki -- Kawai, Shingo (河合, 真吾) (カワイ, シンゴ) -- Okamura, Hideo -- Nishida, Tomoaki (西田, 友昭) (ニシダ, トモアキ)

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