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タイトル: Treatment of tetracycline antibiotics by laccase in the presence of 1-hydroxybenzotriazole
著者: Suda, Tomoyo
Hata, Takayuki
Kawai, Shingo
Okamura, Hideo
Nishida, Tomoaki
掲載誌名: Bioresource technology
出版者: Elsevier
巻: 103
号: 1
開始ページ: 498
終了ページ: 501
出版日付: 2011-10-20
権利: Copyright © 2011 Elsevier Ltd. All rights reserved.
NDC: 464
抄録: Tetracycline antibiotics are widely used in human and veterinary medicine; however, residual amounts of these antibiotics in the environment are of concern since they could contribute to selection of resistant bacteria. In this study, tetracycline (TC), chlortetracycline (CTC), doxycycline (DC) and oxytetracycline (OTC) were treated with laccase from the white rot fungus Trametes versicolor in the presence of the redox mediator 1-hydroxybenzotriazole (HBT). High performance liquid chromatography demonstrated that DC and CTC were completely eliminated after 15min, while TC and CTC were eliminated after 1h. This system also resulted in a complete loss of inhibition of growth of Escherichia coli and Bacillus subtilis and the green alga Pseudokirchneriella subcapitata with decreasing tetracycline antibiotic concentration. These results suggest that the laccase-HBT system is effective in eliminating tetracycline antibiotics and removing their ecotoxicity.
ISSN: 09608524 OPAC
E-ISSN: 18732976 OPAC
出版者DOI: 10.1016/j.biortech.2011.10.041   
PMID: 22071243
NII書誌ID: AA11522750 OPAC ciniib
バージョン: author
出現コレクション:06. 雑誌論文・記事(Journal Article, Article, Preprint)

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Others By: Suda, Tomoyo -- Hata, Takayuki -- Kawai, Shingo (河合, 真吾) (カワイ, シンゴ) -- Okamura, Hideo -- Nishida, Tomoaki (西田, 友昭) (ニシダ, トモアキ)



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