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Title: Leccinine A, an endoplasmic reticulum stress-suppressive compound from the edible mushroom Leccinum extremiorientale
Authors: Choi, Jae-Hoon
Ozawa, Nobuhiko
Yamakawa, Yasuhiro
Nagai, Kaoru
Hirai, Hirofumi
Kawagishi, Hirokazu
Journal Title: Tetrahedron
Publisher: Elsevier
Journal Volume: 67
Journal Issue: 35
Start Page: 6649
End Page: 6653
Issue Date: 2011-09
Rights: Copyright © 2011 Elsevier Ltd. All rights reserved.
NDC: 464
Abstract: LeccinineA (1) along with a known compound (2), were isolated from the edible mushroom Leccinum extremiorientale. The structure of 1 was determined by the interpretation of spectral data. LeccinineA showed protective activity against endoplasmicreticulumstress-dependent cell death. Seven analogues (3–9) of 1 were synthesized in order to evaluate the structure–activity relationship, and the result indicated that the formamide group of 1 was indispensable for the activity.
ISSN: 00404020 OPAC
DOI: 10.1016/j.tet.2011.05.052   
Journal NCID: AA00861787 OPAC ciniib
Textversion: author
Appears in Collections:11. 雑誌論文・記事(Journal Article, Article, Preprint)

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Others By: Choi, Jae-Hoon (崔, 宰熏) (チェ, ジェフン) -- Ozawa, Nobuhiko -- Yamakawa, Yasuhiro -- Nagai, Kaoru -- Hirai, Hirofumi (平井, 浩文) (ヒライ, ヒロフミ) -- Kawagishi, Hirokazu (河岸, 洋和) (カワギシ, ヒロカズ)

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