Shizuoka University REpository  title image 
morning
day
evening
night
shizuppy
 

SURE: Shizuoka University REpository >
06. 農学部・農学研究科 = Faculty of Agriculture >
06. 雑誌論文・記事(Journal Article, Article, Preprint) >

このアイテムの引用には次の識別子を使用してください: http://hdl.handle.net/10297/6750
Bookmark and Share

このアイテムのファイル:

ファイル 記述 サイズフォーマット
120808001.pdf177.26 kBAdobe PDFサムネイル
見る/開く

タイトル: Progesterone Is a Sperm-Releasing Factor from the Sperm-Storage Tubules in Birds
著者: Ito, Tomomi
Yoshizaki, Norio
Tokumoto, Toshinobu
Ono, Hiroko
Yoshimura, Takashi
Tsukada, Akira
Kansaku, Norio
Sasanami, Tomohiro
掲載誌名: Endocrinology
出版者: Endocrine Society
巻: 152
号: 10
開始ページ: 3952
終了ページ: 3962
出版日付: 2011-08-02
権利: Copyright © 2011 by The Endocrine Society
NDC: 464
抄録: Because of the presence of sperm-storage tubules (SST) in the utero-vaginal junction (UVJ) in the oviduct, once ejaculated sperm have entered the female reproductive tract, they can survive for a prolonged time in domestic birds, although the specific mechanisms involved in the sperm uptake into, maintenance within, and controlled release from the SST remain to be elucidated. In this report, we provide evidence that progesterone triggers the release of the resident sperm from the SST in the UVJ. The ultrastructural observation of the SST indicated that the resident sperm are released from the SST around 20 h after oviposition. When laying birds were injected with progesterone, most of the sperm were released from the SST within 1 h of injection. In situ hybridization analyses demonstrated the presence of the transcripts of membrane progestin receptor α in the UVJ, and the translated proteins were detected in the UVJ extracts by Western blotting. Moreover, the number of secretory granules in the SST epithelial cells fluctuates during the ovulatory cycle, and the progesterone administration mimics this phenomena. A binding assay using [(3)H]-progesterone indicated the presence of a high affinity, limited capacity, saturable and single binding site for [(3)H]-progesterone in the membrane fraction of the UVJ, and this receptor did not interact with the synthetic antiprogestin RU486. These results demonstrated for the first time that the progesterone stimulates the release of the resident sperm from the SST and that the release of the sperm might occur via membrane progestin receptor α-mediating signal transduction.
E-ISSN: 19457170 OPAC
出版者DOI: 10.1210/en.2011-0237   
PMID: 21810949
NII書誌ID: AA12024486 OPAC ciniib
関連リンク: http://endo.endojournals.org/content/152/10/3952.short
バージョン: author
出現コレクション:06. 雑誌論文・記事(Journal Article, Article, Preprint)

Google™ Scholar: Cited By - Related - Other Copies

Others By: Ito, Tomomi -- Yoshizaki, Norio -- Tokumoto, Toshinobu (徳元, 俊伸) (トクモト, トシノブ) -- Ono, Hiroko -- Yoshimura, Takashi -- Tsukada, Akira -- Kansaku, Norio -- Sasanami, Tomohiro (笹浪, 知宏) (ササナミ, トモヒロ)

本リポジトリに登録されているコンテンツの著作権は,執筆者,出版社、学協会などが有します。著作権者はコンテンツにより異なります。
本リポジトリに登録されているコンテンツの利用については,著作権法に規定されている私的使用や引用などの範囲内で行ってください。
著作権に規定されている私的使用や引用などの範囲を超える利用を行う場合には,著作権者の許諾を得てください。ただし,著作権者から著作権等管理事業者(学術著作権協会,日本著作出版権管理システムなど)に権利委託されているコンテンツの利用手続については,各著作権等管理事業者に確認してください。

 

Powered by DSpace Software Copyright © 2002-2007 MIT and Hewlett-Packard - ご意見をお寄せください